CeliacAdvanced | CeliacDisease | CeliacAdvanced | Protection |
Nathaniel Ethan |
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Interpreting Bloodwork Anti-Gliadin Antibodies........(AGA).......IgA A result of less than 20 is considered a negative result for the antibody. A result of 20-30 is considered to be a "weak positive". A result of more than 30 is considered to be a moderate or strong positive. Virtually 100% of those with POSITIVE IgA anti-gliadin antibodies have celiac. Anti-Gliadin Antibodies........(AGA).......IgG Over 90% of those with POSITIVE IgG anti-gliadin antibodies have celiac. (Note: Up to 10% of those with positive IgG anti-gliadin antibodies do NOT have celiac.) Anti-Endomysium Antibodies........(EMA).......IgA Virtually 100% of those with Celiac are POSITIVE for IgA antiendomysium antibodies after eating gluten. 100% of those with Celiac on carefully restricted diets are NEGATIVE for IgA antiendomysium antibodies. An absence of these antibodies in a person who eats gluten is considered definitive that they are NOT Celiac. Anti-Reticulin Antibodies........( ).....IgA There are five types of antireticulin antibodies. Only one of these is associated with celiac disease, though it is very specific for celiac disease. Virtually 100% of those POSITIVE for this antibody after eating gluten have Celiac. Rare Celiac patients who are also IgA deficient will make IgG antibodies. In this case, only the AGA can be used to correctly diagnose Celiac. The presence of two of these three antibodies- Circulating IgA-gliadin, antireticulin, and antiendomysial- raises the probablity of definitive diagnosis even more. http://www.fbr.org/publications/resguide99/rg-tl04.html http://www.aetna.com/cpb/data/CPBA0561.html http://www.fbr.org/publications/resguide99/ The Development & Diagnosis of Celiac Celiac is an autoimmune disease which may occur as the result of a viral infection in people who are already genetically predisposed to Celiac. http://www.enabling.org/ia/celiac/predic.html
Within the confines of a discussion of Celiac, the term gluten is used to refer to "peptides derived from prolamins (proteins) that include the harmful amino acid sequences found in wheat." Enter content here |
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